Endocrine Abstracts

The intrauterine foetal environment is crucial for foetal survival and long term health. The insulin-like growth factors (IGF)-I and -II have a predominant role in fetal growth and development. Insulin-like growth factor 1 (IGF-1) is an anabolic hormone with several biological activities, such as proliferation, mitochondrial protection, cell survival, tissue growth and development.Aims & Objectives: To find the association of Maternal insulin Growth ...

This study was planned to investigate the relationship between birth weight and IGF1, IGF binding protein-3 (IGFBP3), in neonates with normal growth (appropriate for gestational age: AGA) and retarded growth (small for gestational age: SGA). A total of 200 mothers were recruited, 120 serum samples were maternal and collected between gestational age of 32-38 weeks, 80 were cord blood from SGA and AGA fetus collected soon after delivery. 98 maternal samples and 48 cord blood sam...